CSB331H1 Lecture Notes - Lecture 3: Desmosome, Ctnnd1, Adherens Junction

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Lecture 3: desmosomal junctions (slides 1 to 20) Cannot form tight junctions and desmosomes without adherence junctions (lecture 2) Desmosomal junctions: primary function: impart mechanical strength and rigidity to tissues found in cardiomyocytes and epithelia. lock it down the basal lamina. Conserved domains are meant to mediate universal interactions. Functional diversity in interacting with intermediate filaments and intracellular signal transduction event is arised from the endodomain.

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