CSB346H1 Lecture Notes - Lecture 5: Antidromic, Neuroglia, Solitary Tract

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Co2 is sensed by the respiratory system such that it affects respiration/ventilation. cells in the brain, could be neurons, gila, that appear to detect changes in co2 level such that ventilation increases. As co2 level goes up, ventilation goes up. Co2 levels are principly detected by chemoreceptors, some of them being centrally located and some peripherally. In contrast to o2 level, which is primarily detected by peripheral chemoreceptors. Stop heart and take your blood and oxygenate it and they take. But what drives you to inspire o2 isn"t necessarily o2 level. Amount of o2 in arteries and veins is only 25% diff in terms of saturation level, so you still have 75% o2 available. What was really important in this experiment is that co2 is actually the drive for you to breath in instead of o2 level. As soon as you help the lamb remove some of the co2 level, not o2 level, you"re not.

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