CSB346H1 Lecture Notes - Lecture 4: Control Of Ventilation, Phrenic Nerve, Hypoglossal Nerve

• School: UTSG
• Department: Cell and Systems Biology
• Course: CSB346H1
• Professor: John Peever

Document Summary

Rhythm must be 1) transmitted in an orderly sequence to the respiratory muscles (airway vs diaphragm, inspiratory vs expiratory) and 2) respond to inputs from other brain regions (eg. limbic system) and peripheral afferents (eg. pulmonary receptors) Network of interneurons that communicate with each other with no other input from rest of brain to produce a predictable and repetitive motor pattern such as breathing, locomotion, swallowing, chewing and eye movements. The rg must activate a specific group of motor neurons in a certain sequence; in breathing, inspiratory neurons are activated before expiratory neurons. Suzue showed that neither lungs nor respiratory muscles were source of respiratory rhythm. Suzue also showed that the respiratory rhythm generated by the en bloc preparation responds to low and high ph by increasing and decreasing respiratory frequency further evidence that the in vitro. Rrg could not only generate but also modulate breathing.