HMB265H1 Lecture : Notes taken during lecture

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redtermite204

15 Feb 2011

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Huntington"s disease once one generation doesn"t have it, the disease is eliminated in the. Need to find where it is, before they can do anything about it. Find patterns of inheritance, and move from genetics to molecular studies and biochemistry. Took decades to find the gene and how it works to find a cure how do you isolate the gene of interest using genetic tools. Human genome main funding incurred by medical implications. having genetics pave a road map makes the process faster. Two different funding one public, one privately funded. collins hierarchical approaches sequence clones after having ordered them. venter whole genome dive right in. cannot read sequence of chromosome from start to finish **: cut copies of genome, using overlapping areas to put the fragments together. can"t get any further because many sequence of repetition: not sure of true overlap. With hd, had no idea of gene and where it was.

Related Questions

What are two approaches to cloning the human orthologs of the yeast genes?

Select the two correct answers.

a) This could be done by position cloning of genes of interest after creating a genetic map using molecular markers.

b) This could be done by using the yeast genes as a probe to screen a human cDNA library.

c) This could be done by tagging the human genes of interest using transposons.

d) This could be done by using the sequence of yeast genes to create primers to amplify the human genes by PCR.

byzantiumchinchilla839

The ___ was a massive scientific undertaking meant to identify and sequence all of the genes found In a human cell. This is just one example of ______, the branch of biology that studies whole_____ , which are the complete sets of DNA found within organisms. One of the interesting conclusions from this project was that only about 1.5% of human DNA encodes for_____ . Although it was groundbreaking for its time, it is now fairly routine to completely sequence the DNA of an organism using the ______ method. In this method, the DNA is chopped up with restriction enzymes, the fragments are sequenced, and then they are reassembled into one continuous sequence. Through such analyses, scientists are learning much about human DNA and its relation to other species.

Terms:

proteins

genomics

genomes

genetic engineering

whole-genome shotgun

Human Genome Project

lavendercamel236

How have advances in technology accelerated genetic discoveries?

A. Any phenotype can now be assigned to a mutation.

B. Comparing expression patterns of different cells demonstrates how proteins are related.

C. Sequencing of genomes allows for the understanding of how all genetically controlled diseases arise.

D. Genome sequencing allows for the comparison of the genomes of individuals within a species and possibly determine how some phenotypes arise.

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HMB265H1 Lecture : Notes taken during lecture

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