HMB300H1 Lecture Notes - Lecture 7: Karyotype, Home Shopping Network, Cytochrome C
Document Summary
1st introduced and used by sydney brenner (1963) to study development and neurology. Adults are ~1mm long (small) They can be grown on agar plates with lawn of bacteria. They have a short generation time- 3 days from egg- laying to adulthood, brood size > They are transparent, so internal anatomy can be easily observed. 2 different forms: hermaphroditic form and male form. 5 autosomes i- v and x (6 total) Hermaphrodite produces many progeny- - - 300 worms: capable of self- fertilization. Adult hermaphrodites have 959 somatic cells (xx karyotype) while males (xo karyotype) have. Mitochondria is the initiator for this pathway in neurons. If mitochondria is healthy, cytochrome c and other pro- apoptotic factors will stay inside mitochondrial matrix. If released into cytoplasm = starts cell death pathway.
