MGY378H1 Lecture Notes - Hepatitis D, Hepatitis B, Hdv
3 Jun 2013
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Document Summary
Outside of virus identical to hepatitis b virus envelope and inserted into env are surface antigesn of hepb. Hepd predominantly has small antigen on its surface. Hepd viral rna that is single stranded that is circular and negative sense virion capsid structure partially dsdna two antigens in surrounding genome, called delta antigen large and delta antigen small. D piggybacks on b virus consists of lipid bilayer. 70% base paired self-complementary to a lot of itself have end loops. Viroid element: commonly found in plants, does not need hepb to replicate itself just need hepb to allow assembly of virion. Infectious nucleic acids particle to allow transmission from one cell to next, from one host to the next. Transmission by the same route sex, exposure to infected blood, perhaps within families with high incidence of hepb and d. Impact of infection depends on when you acquire the virus. Left both simultaneously majority fully recover and have immunity to both agents.
