NFS284H1 Lecture Notes - Lecture 16: Impaired Glucose Tolerance, Low Birth Weight, Birth Weight
14 Mar 2018
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Is most of the weight lost after giving birth: yes. Why is some fat not lost: needed to fuel lactation. Is weight loss recommended during pregnancy: no, should be done before pregnancy for obese women. Are canadians gaining more weight now during their pregnancies: yes. Are additional calories required: yes extra 350-450kcal, e. g. extra glass of milk or piece of toast. What is the relationship between maternal weight gain and infant birthweight: both positively correlated, too much or too little weight gain is harmful. Low birth weight: changes in genotype -> epigenotype, spend less energy -> weight gain in energy rich environment -> adult obesity. Genotype vs epigenotype: snps - genotype, silencing - epigenotype, e. g. In utereo famine exposure increases risk of: obesity, cvd. Impaired glucose tolerance: similar results when mother smokes during pregnancy or has high insulin levels. Is reduced breast feeding during infancy a risk factor in obesity: yes.
