PCL200H1 Lecture Notes - Lecture 2: Μ-Opioid Receptor, Reinforcement, Nicotine

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Survival of species: repeat the things that keep us alive (&keep our progeny alive) avoid things that get us killed pain. Innate fears learned fears food (high calorie) cold water: shelter & warmth, entertainment (stories, social interactions & approval love and sex. Dopamine brain uses dopamine system to mark when something is good or bad dopamine neurons are always ring at a steady rate, when something good happens their. De ning addiction: de ned as a compulsion yo take a drug (or engage in activity) despite adverse consequences this is different from physical dependence. Who is vulnerable to addiction? people who consume addictive drugs environmental risk factors - prevalence of drug use in community, peer group, family. Early stage of addiction recreational drug use - intoxication high , positive reinforcement - intoxication wears off, dysphoria - drug seeking. Compulsive drug use, tolerance - withdrawal symptom relief, acute withdrawal, drug seeking.

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