PCL102H1 Lecture Notes - Lecture 21: Battle Of Basian

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This is a very biomarker driven trial where we use biomarkers to make decisions. In these trials we are loking for the best biomarkers. A complete response is looking under a microscope and not being able to see any cancer present. Another outcome endpoints how long there is survival before there is occurrence. It was sponsored by a group of companies. By allowing the flexibility of haxing these different drugs, it allowed the researchers to proceed and not having to stop to write a whole new protocol. The role of the companies is that they would donate the drugs to the trial. This is a phase 2 trial because its testing efficacy. This study was looking for the best biomarkers. Each cube represents how many people there are. Top half is tradntinal clinical trial, bottom half is adapted clinical trial. In the adapted, its testing multiple drugs at once, and the control is standard of care and is not placebo.

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