PHY100H1 Lecture Notes - Lecture 2: Synaptic Plasticity
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PHY100H1 Full Course Notes
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Postsynaptic responses may be slow or fast: fast synaptic responses are always associated with the opening of ion channels. In the simplest response, the neurotransmitter binds to and opens a receptor-channel on the postsynaptic cell, allowing ions to move between the postsynaptic cell and the ecf: the resulting change in membrane potential is called a fast synaptic. Potential because it begins quickly and lasts only a few seconds: if the synaptic cell is depolarizing it is called an excitatory. Postsynaptic potential (epsp) because it makes the cell more likely to fire an ap: if the synaptic potential is hyperpolarizing it is called an inhibitory. Postsynaptic potentia (ipsp) because hyperpolarization moves the membrane potential away from threshold and makes the cell less likely to fire an. From multiple neurons: the combination of several nearly simultaneous graded potentials is called spatial.