PSL300H1 Lecture Notes - Lecture 24: Anterior Pituitary, Linear Function, Insulin-Like Growth Factor 1
Document Summary
Pathway & regulation of growth hormone v sleep, exercise, acute stress stimulate gh v gh is released in pulses, more released at night v the hypothalamus has specialized neuronal cells that release. Growth hormone releasing hormone (ghrh: ghrh stimulates the anterior pituitary to release. Psl300 human physiology i v when gh gets released into the body, its targets are all throughout the body: include bone and muscle. Targets bone and soft tissue to stimulate growth: gh also goes to the liver, which releases igf-1. Also known as somatostatin v somatostatin / ghih inhibits gh. Psl300 human physiology i v linear growth is required to grow taller: bones have to elongate, the whole body also needs grow in terms of increasing proliferation. This is hyperplasia: increasing the proliferation of cells also requires the increase of more proteins that need to be synthesized.
