PSL300H1 Lecture Notes - Lecture 26: Calcitriol, Rickets, Vitamin D Deficiency
Document Summary
Actions of calcitriol v digestive tract: increases calcium absorption v kidney, increases calcium reabsorption v overall effect, increase plasma calcium concentration v calcitriol increases calcium absorption, calcium is ingested through different dietary sources. Absorbed through the small intestine v a lot of calcium supplements include vitamin d: in order for the calcium supplement to be effectively absorbed into the body, the body needs activated vitamin d as well. Psl300 human physiology i v at the level of the kidney, calcitriol increases calcium reabsorption: this way, calcium is not lost through urine. Vitamin d deficiency v may be caused by: lack of sunlight, lack of adequate absorption in the small intestine (celiac), kidney or liver problems (processing of vitamin d) Condition where the growth plates become softened. Bones are more likely to bow under the weight of the child: osteomalacia in adults.
