PSL301H1 Lecture Notes - Lecture 16: Breathing, Pulmonary Function Testing, Elastic Fiber
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PSL301H1 Full Course Notes
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Surfactant and tension: airway resistance and flow, measuring lung function. Shortly after birth, baby begins to breathe rapidly (tachypnea) and has rapid heart rate (tachycardia), grunts when she expires and has cyanosis (extremities are blue). Lacks surfactant, leading to low compliance in the lungs. This makes it harder for her lungs to breathe and move. Inject artificial surfactant into the lungs to increase the compliance. Once baby develops to term, body"s own type ii cells in lungs would produce their own surfactant. 20yo john just had a pulmonary function test. Likel(cid:455) inc(cid:396)eased ai(cid:396)wa(cid:455) (cid:396)esistance since he can"t e(cid:454)pel ai(cid:396) as (cid:395)uickl(cid:455) In this case, john has asthma which tends to close off the airways. Degree the lungs will comply by changing their volume when subjected to change in intrapleural pressure: influenced by elastin fiber network and surface tension in the alveoli. Influenced by type of flow and airway diameter. Elastic fibers in the ecm between the cells.
