PSL301H1 Lecture Notes - Lecture 19: Fluid Compartments, Osmotic Concentration, Molality

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PSL301H1 Full Course Notes
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PSL301H1 Full Course Notes
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Human kidney physiology: lecture 1 body fluid compartments. What does the kidney do: maintains normal volume and composition of body fluid compartments, excretes waste products from the body, helps maintain blood pressure, hemoglobin levels and calcium levels through hormone secretion. Objectives: body fluid compartments and what determines their volume and composition, factors that regulate glomerular filtration, regulation of excretion of sodium, potassium, water and h+ by tubules, physiology of renin/angiotensin, erythropoietin and vitamin d. Some definitions: nephro = renal = kidney, solutes: particulates dissolved in a water solution (na, p, glucose, osmolatlity: the concentration of solutes in water which generates an osmotic force (the sum of all. Ions (electrolytes): charged solutes (cations +, anions -) small solutes) Plasma is the most important: plasma separated by capillary wall from interstial fluid which is separated by a cell membrane. Women compared to men (50% vs 60%) men normally have more muscle. Older compared to younger lower total body water, because less active.

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