PSL301H1 Lecture Notes - Lecture 25: Bicarbonate Buffer System, Ascending Limb Of Loop Of Henle, Sodium Bicarbonate

• School: UTSG
• Department: Physiology
• Course: PSL301H1
• Professor: French, Gramolini, Richardson, Wong

Document Summary

Stomach has the most concentrated ph: there is no such thing as normal urine ph, ph allows the conversion of a wide range of. Buffers limit the change of h+ concentration when an acid is added to a solution: ph would be 3! What prevents severe acidosis when we eat meat: buffers, examples of buffers in humans. If for some reason, there"s a disorder where bicarbonates go down, body can compensate by. Ignoring carbonic acid (which is not measured in the laboratory) having pco2 decrease. Increasing bicarbonate decrease [h+] and increases ph (alkalosis) Increasing pco2 increases [h+] and decreases ph (acidosis: bicarbonate can be increased or decreased by the kidney, co2 can be increased or decreased by the lungs (alveolar ventilation, ph hco3. If a disorder causes a fall in bicarbonate (and acidosis) the lungs can lower co2 and bring ph towards normal (compensation) The 4 acid-base disorders and compensation: because both sides of the equilibrium can be independently regulated.