Anatomy and Cell Biology 3319 Lecture Notes - Lecture 4: Alar Plate, Neural Crest, Neuroepithelial Cell
5 Oct 2016
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Lecture 4: development of the brain and spinal cord. Describe the process of neural tube formation (neurulation) Describe the stages of development of the nervous system. Determine the embryonic origins of adult brain structures. Begins at the end of week 3 (around day 17) of embryonic development, and continues during week 4. Dorsal folding along the longitudinal axis (i. e. notochord direction) of the embryo is induced by underlying notochord. Begins with formation of neural plate by thickening of ectoderm (day 17: thickening of the endoderm is induced by the notochord. Next, the neural groove begins to form by neural folding of the neural plate (day 19): it makes up lumen of the neural tube later. Neural folds are the ridges where the groove begins to dip inwards (i. e. the peaks) formed by the ectoderm folding up: these are the parts that meet to close the neural tube. Occurs at same time as lateral and longitudinal folding of the embryo.
