Biochemistry 2280A Lecture Notes - Lecture 20: Extrachromosomal Dna, Cellular Respiration, Oxidative Phosphorylation
20 Jan 2020
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Mitochondrial structure: has 2 membranes, outer membrane, has many pores in it. Is freely permeable to most solutes of low molecular weight. It is believed they evolved from bacteria that lived symbiotically in primitive cells because they have their own dna, 2 membranes like bacteria, and reproduce by dividing. Mitochondrial respiration: net result of bioenergetic reactions in mitochondria is to convert pyruvate and o2 into. Co2 and h2o in a process called respiration. Pyruvate + o2 co2 + h2o: the o2 we inhale when we breath (physical respiration) is used as the final electron acceptor for mitochondrial respiration. 1: there are 2 stages to pyruvate oxidation, decarboxylation of pyruvate and addition of coenzyme a to form acetyl-coa, oxidation of the acetyl group of acetyl-coa by the citric acid cycle. Coenzyme a: a carrier molecule used to move acyl groups (r-c=o) around cells. ***be able to identify this; note the thiol (s-h group)
