Biochemistry 2280A Lecture Notes - Lecture 1: Trigonal Planar Molecular Geometry, Valence Electron, Glycosidic Bond

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Cells function is based upon organelles, cellular systems and macromolecules. Only elements able to form large complex molecules. Hydrogen = 1 bond, carbon = 4, oxygen = 2, nitrogen = 3, sulfur = 2, phosphorus =5. An atom"s ability to form molecules has to do with the atoms in the valence shell: ex. Hydrogen has 1 valence electron, able to share and form bonds to become full, whereas helium has 2 valence electrons and does not. Biological molecules are not actually 2d, they take 3d shapes to minimize repulsion between electrons and surrounding elements: use line diagrams (ex. wedge-dash representation) to show 3d structure when drawing, different diagrams may look different, just shaped differently. Single bonds allow rotation: rotation around single bonds changes the conformation of the molecule, not all conformations are equally likely (energetically favorable). If they bring electrons closer together, they are more likely to be unfavourable.

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