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Lecture

Biochemistry 2280A Lecture Notes - Pentose Phosphate Pathway, Glycogen Synthase, Allosteric Regulation


Department
Biochemistry
Course Code
BIOCHEM 2280A
Professor
Derek Mc Lachlin

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Overview of energy metabolism
Glucose-6-phosphate
Pyruvate
Acetyl-CoA
Glycogen
Lactate
Ketone bodies
Fatty acids
Triacylglycerols
NAD+
NADPH
NADH
FADH2
UTP
Pi NADPH
Ribose-5-phosphate
Nucleotides
DNA, RNA
Amino acids Proteins
Cholesterol
Membrane lipids
NADH
ATP Pi
ATP
NADH
ATP
ATP CO2
NADH, FADH2
GTP
O2
H2O
Glucose
ADP + Pi
NAD+, FAD
NADH

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Topic 12
Carbohydrate metabolism

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Topic 12 learning objectives
Identify the different metabolic fates of glucose-6-
phosphate, and how these pathways are related
Explain in general terms how glycogen is
synthesized and degraded
State the net reactions of glycolysis and
gluconeogenesis (including stoichiometries)**
State the metabolic circumstances under which
glycogen synthesis, glycogen degradation,
glycolysis, and gluconeogenesis are favoured,
without memorizing individual regulators
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