Biology 1002B Lecture Notes - Cystic Fibrosis, Lipid Bilayer, Membrane Fluidity

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Cystic fibrosis: a recessive genetic disease caused by mutation in the cftr gene. Cystic fibrosis transconductance regulator (cftr): a chloride ion active. Active transport: transport against a concentration gradient requiring energy. Atp-binding cassette (abc) transporter: transmembrane proteins that utilize. Fatty acid: a carboxylic acid with a long carbon tail. Saturated: every carbon has the maximum amount of hydrogen atoms (2) Membrane fluidity: the viscosity of the lipid bilayer of a cell membrane. Hydrogenation: the addition of a hydrogen to a fatty acid. Desaturase: enzymes catalyzing the formation of double bonds in fatty acids. Membrane permeability: the quality of a membrane that allows for diffusion. Simple diffusion: diffusion along a concentration gradient through a membrane. Facilitated diffusion: diffusion down a concentration gradient through a molecule specific protein pore . Atp hydrolysis to transport substances across the membrane transporter that functions to keep epithelial linings moist the cftr causing cystic fibrosis (70% of all cases)

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