Biology 2382B Lecture Notes - Lecture 8: Cyclin-Dependent Kinase, Ubiquitin Ligase, Cyclin
16 Aug 2017
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Document Summary
Mpf and control of g2 m transition. Essential mechanism by which all living things reproduce and pass on genetic information to next generation of cells. Ensures that dna in each chromosome is faithfully replicated to produce 2 copies. Replicated chromosomes must be accurately distributed (segregated) to 2 genetically identical daughter cells. Cell cycle ordered sequence of events in which a cell duplicates its chromosomes and divides into two genetically identical cells. Four phases g1 s g2 m. G1-s-g2 = interphase, the cell increases in size: longest period of cell cycle. A cell at any point in time, particularly in culture conditions, won"t look like it has much going on. Most dramatic events observed microscopically occur during the m phase. Generalized growth and metabolism of the cell: want relaxed chromatin (garden hose) in order to transcribe it. Where most cells arrest when not dividing (go) Variable length (~11 hours in mammalian cells)
