Biology 2382B Lecture 14: Cummings Lecture 9-Cell signalling
16 Aug 2017
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Document Summary
Basic principles of cell signaling and gpcr system. Gpcr, g proteins, types of ga, effectors, second messengers. Essential mechanism by which all living things reproduce and pass on genetic information to next generation of cells. Ensures that dna in each chromosome is faithfully replicated to produce 2 copies. Replicated chromosomes must be accurately distributed (segregated) to 2 genetically identical daughter cells. Cell cycle ordered sequence of events in which a cell duplicates its chromosomes and divides into two genetically identical cells. Four phases g1 s g2 m. G1-s-g2 = interphase, the cell increases in size: longest period of cell cycle. A cell at any point in time, particularly in culture conditions, won"t look like it has much going on. Most dramatic events observed microscopically occur during the m phase. Generalized growth and metabolism of the cell: want relaxed chromatin (garden hose) in order to transcribe it. Where most cells arrest when not dividing (go)
