Biology 2382B Lecture Notes - Lecture 12: Caspase 1, Caspase, Intermembrane Space
7 May 2019
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Ultrastructure features of apoptosis: programmed cell death to ensure: Proper homeostasis in adults: cell shrinks, dna compaction and broken down into apoptotic bodies for degradation. Intercellular contents may expose to body which trigger immune response. Apoptosis: contents remain encapsulated for degrade: elegans, defined number of cells, transparent, easily manipulated. Mutated don"t get cells dying off (more cell as adult cause cells that should have died didn"t) Caspases in apoptosis: ced3 encode from protease caspase . Initiator caspase: activate by dimerization, cleave off piece of effector caspases. Cytochromo c: release from intermembrane space of mitcho during apop.
