Biology 2581B Lecture Notes - Lecture 10: Base Pair, Restriction Enzyme, Wild Type

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Finding a gene sequence based on its phenotype. Can be done with and without mapping information: without will need other information. Hemophilia a: no mapping information particular genotype that you are looking at. In both cases you have a disease phenotype and you want to know what the underlying gene or protein is that is causing the particular defect. Have the whole genome sequences do not know which one of the thousands of genes is causing the. Two types a and b: sill have to link a particular gene to a phenotype. Hemophilia a: co segregate with color blindness: people who had hemophilia a also had colour blindness, the two locations are close to each other on the genome because they seem to be inherited. Hemophilia b: the two characteristics (hemophilic and color blindness) are not appearing in the same people.

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