Biology 3592A Lecture Notes - Lecture 2: Mendelian Inheritance, Gametogenesis, Prophase

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21 Sep 2016

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W/ meiosis ii difference is that its haploid. Another difference is w/ mitosis the 2n number stays the same, meiosis it is reduced 2n n. Shift from 2n-n occurs in the 1st division meiosis 1 (reductions) Have only one copy the maternal or paternal you will have 2 chromatids however. Recombination always takes place (~4/chrome) if they have not gone under recombination then they will not be able to segregate properly. Only difference is that this is haploid (only one parental chromosome) You get one maternal and one paternal chrome but not really b/c recombination cross over in prophase 1. In theory its 50% of each but reality = not exactly. Crossing over occurs at prophase 1 and then lining up at metaphase. Non sis chromatids coming tog at centromere. Maternal and paternal non sis chromatids line up (2/4 from pair of homologous chromosomes)

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1). Explain the significance of the fact that gametes contain half of the chromosome complement of somatic cells. Tell me something about variation, if you have a sibling (if you don't imagine you do) - how is your sibling's genetic make-up similar and/or different from yours? What about your mom and dad?

2). Explain the terms reductional division and equational division. What is reduced or kept equal? To which nuclear divisions do these terms refer?

3). What is the diploid number (2n = ?) of an organism if it has
a) 12 chromosomes at Anaphase of Mitosis?
b) 12 chromosomes at Anaphase I of Meiosis?
c) 12 chromosomes at Anaphase II of Meiosis?

4). Compare/contrast Metaphase I of Meiosis with Metaphase of Mitosis.

5). What are the two mechanisms of variation in Meiosis, and during which stage(s) does each occur?

6). Draw a diagram of a bivalent and label the following parts: centromere, sister chromatids, non-sister chromatids, homologous chromosomes, chiasma.

7). A diploid cell has 1 pair of acrocentric chromosomes (Chromosome 1) and 1 pair of submetacentric chromosomes (Chromosome 2).
Â· Gene X is on Chromosome 1. Gene Y is on the short arm of Chromosome 2 and Gene Z is on the long arm of Chromosome 2.
Â· The maternal chromosomes have the X, y, z alleles, whereas the paternal chromosomes have the x, Y, Z alleles.
Draw these chromosomes, labeling ALL alleles, as they might appear in Metaphase I of Meiosis.

Title: Meiosis Lab

Part 1: Modeling Meiosis Without Crossing Over (reformat as needed)

Take photos of the following stages of your meiosis bead simulation. Insert and label the following images:

Meiosis 1: Prophase I and Metaphase I

Meiosis 2: Metaphase II and Telophase II

Part 2: Modeling Meiosis With Crossing Over (reformat as needed)

Take photos of the following stages of your meiosis bead simulation. Insert and label the following images:

Meiosis with Crossing Over: Metaphase I and Telophase II

Questions â use the lab Introduction, your textbook and other sources to answer the following.

What is the state of DNA at the end of meiosis I? Are the chromosomes replicated or unreplicated? Diploid or haploid?

Why are chromosomes important?

How are Meiosis I and Meiosis II different?

Name two ways meiosis contribute to genetic recombination or genetic variety.

Why do you use non-sister chromatids to demonstrate crossing over? What would happen if you crossed over sister chromatids?

How many chromosomes were present in your simulation when meiosis I started?

Why is it necessary to reduce the chromosome number in gametes, but not in other cells of an organism?

If humans have 46 chromosomes in each of their body cells, determine how many chromosomes you would expect to find in the following:

Sperm	Egg	Daughter cell after mitosis	Daughter cell after meiosis

Investigate a disease that is caused by a chromosomal mutation due to nondisjunction. When does the mutation occur? What chromosome is affected? What are the consequences?

Question 1 Select one answer. 10 points Crossing over occurs:_______________.

during both meiosis I and meiosis II

during mitosis but not meiosis

during meiosis II only

during meiosis I only

Question 2 Select one answer. 10 points Homologous pairs ofchromosomes line up at the center of the cell in during which stageof meiosis?

Metaphase I,

Metaphase II,

Telophase I,

Telophase II

Question 3 Select one answer. 10 points A haploid organism hashow many copies of each chromosome?

1, 2, 3, 4

Question 4 Select one answer. 10 points The sister chromatidsseparate during which stage of meiosis?

Anaphase I, Anaphase II, Prophase I, Prophase II

Question 5 Select one answer. 10 points Describe the importanceof independent assortment: ________________________.

will assort independently of each other,

will sort to the same gamete,

are called alleles

All of these are true

Question 6 Select one answer. 10 points How many differentgametes are produced by a cell with the genotype AABb?

1, 2, 3,4

Question 7 Select one answer. 10 points The next two questionsare based on the following information. Part 1 of 2: In beansyellow (Y) is dominant to green (y) and smooth (S) is dominant towrinkled (s). What are the possible genotypes for the offspring ofthe following cross: YySS and YYSs.

Yy, SS, YY, Ss

YYSS, YySS, YYSs, YySs

YYSS, YYss, yySS, yyss

YS, yS, YS, yS

Question 8 Select one answer. 10 points Part 2 of 2: In beanswith yellow (Y) dominant to green (y) and smooth (S) dominant towrinkled (s): What are the phenotypes for the offspring in theexample in the previous question?

100% green wrinkled,

50% yellow smooth and 50% greensmooth,

100% yellow smooth,

50% yellow smooth and 50% yellowwrinkled

Question 9 Select one answer. 10 points Alleles are differentversions of a _______________.

chromosome,

genotype,

phenotype,

gene

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Biology 3592A Lecture Notes - Lecture 2: Mendelian Inheritance, Gametogenesis, Prophase

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