Biology 3592A Lecture Notes - Lecture 6: Mitosis, Meiosis, Centromere
28 Sep 2016
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Lecture 6 cytogenetics 2 chromosome rearrangements. Missing chromosome, added chromosome, or just wrong number of them aneuploidy of people that can still be born (not detrimental enough that they can"t live) More aneuploidy happening with x and y chromosomes then autosomes. Notion of x inactivation (one x in females shut down) less detrimental when this chromosome gets shut down reason for more aneuploidy in every organism there"s a way to comprise between both sexes. Balanced chromosome abnormality: all the genetic information is still present but it is rearranged. Unbalanced chromosome abnormality: some chromosome material is missing or in excess. * makes sense that balanced translocation will have less of a detrimental effect then unbalanced. When talking about mutations at molecular level quality. At cytogenetical level abnormalities quantitively not qualitively alter gene expression. Not actually altering any proteins, they"re producing the same thing difference is there"s either more or less.
