Biology 1001A Lecture Notes - Lecture 6: Prometaphase, Cytokinesis, Chromosome Segregation
1 Apr 2016
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Stages and main characteristics of the stages of mitosis. Prophase: dna condenses into sister chromatids, translation and transcription stop. Prometaphase: nuclear envelope disappears, microtubules attach to replicated chromosomes (only once nuclear envelope has completely dissolved) Metaphase: chromatids line up at the spindle midpoint/metaphase plate. Anaphase: cohesin dissolves and sister chromatids (now called chromosomes) are pulled by motor proteins in kinetochores along spindles to opposite poles of the cell. Telophase: the spindle disassembles, the nuclear membrane reappears and the chromosomes decondense. Ani(cid:373)als: for(cid:373) (cid:272)lea(cid:448)age furrow, deepens and (cid:862)(cid:272)uts(cid:863) (cid:272)ytoplas(cid:373) Stage of cell division, given a micrograph of a dividing cell. What is the role and mechanism of the mitotic spindle? o. Actin filaments are involved in cytokinesis (where the cell pinches) The spindle has two spindle poles on opposite sides of the cell. Fibers called microtubules (made of tubulin proteins) attach to chromosomes" kinetochore proteins after the nuclear envelope is dissolved.
