Biology 1002B Lecture Notes - Lecture 8: Atp Synthase, Electrochemical Gradient, Acetyl-Coa

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Addition on uncoupler: (steepest slope) becomes easy to pump electrons, so many holes i n the membrane that you never establish a ph gradient, protons never go through atp synthase. Because proton pumping is now easy, the rate of electron transport is highest as it can be, nothing stopping the rate of electron transport if you completely uncouple it. No ph difference, no proton motoforce: definition of respiratory control and how it is accomplished (proton gradient). The rate of oxidation of nadh is kept in check if there"s no adp and p around, it is kept pretty low if there"s no substrate to bring the flow to atp synthase. If you add adp and p, you"re releasing the proton gradient, becomes easier to pump electrons, rate of transport goes up: metabolic link(s) between chloroplast and mitochondria. Gets made into a pyruvate and into acetyl coa into the citric acid cycle.

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