Biology 1002B Lecture Notes - Lecture 9: Pattern Formation, Blastoderm, Regulatory Sequence

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Laid down primarily as concentration gradients of regulatory molecules produced by genetic control: gradients of several different regulatory molecules interact to tell a cell or cell nucleus where it is in the embryo. 42. 7e homeotic genes: structure and determining outcomes: homeotic genes of the embryo specify what each segment will become after metamorphosis. Slide 2: nonsense mutation: going from a codon that codes for an amino acid to a stop codon. Slide 3: frameshift mutation: most severe single base pair mutation, translation is done in codons, by 3s, there must be a reading frame, the start codon sets the frame. So if we insert a base or delete a base, we will disturb/shift the frame and every amino acid will be wrong. Mental floss: consider a single base pair insertion into the dna coding for the first exon in the mrna shown.

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