Biology 1002B Lecture Notes - Lecture 16: Nematode, P53, Chromosome

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2:01 am o o o o o o o o o. Eukaryotes start as single cell, develop into multicellular organism. How does a fruit fly get from an egg to an adult? o o o o. Eventually, nuclei migrate to periphery and become cellularized. End up with cells around the outside of the developing embryo. Important for nuclei to know where they are. Blastula o o o o o o o o. In flies, once gastrula develop, they develop into a worm. Then they get hard, crusty, turning into a fly inside the pupi. At each stage of development, notice which proteins are turned on and expressed at which times. What is the expression profile of genes at certain stages. What happens to mutants with certain genes o o o o o. Help nuclei figure out where they are in the embryo. How much of each protein do they have. Bicoid: common at the head, not at the tail.

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