Biology 1002B Lecture Notes - Lecture 8: Sister Chromatids, Haemophilus Influenzae, Alternative Splicing

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Developed by j. craig venter and his associates at celera genomics. Entire genome is broken down into thousands to millions of random, overlapping fragments. Bioinformatics: fuses biology with mathematics and computer science they apply computer operated algorithms for annotation. Bioinformatics is also used to predict the structure and function of gene products and to suggest evolutionary relationships of sequences. 15. 3b genome sequence determination and annotation: genome sequence determination and annotation involves obtaining and analyzing the sequences of complete. Table 15. 1 conclusions: members of the domain bacteria have genomes that vary widely in size. Carsonella ruddii has the smallest known cellular genome of any organism with 182 genes. 182 genes is now known as the minimum amount of genes required for life. Largest bacteria is 80x that: archaean genomes also vary widely in size. Largest known is methanosarcina aceticorans. Yeast has the smallest genome, yet humans have a little more than 3x the number of genes as yeast.

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