Biology 1202B Lecture Notes - Lecture 11: Ribonucleoprotein, Prokaryote, Chromosome
Document Summary
The structure of dna allows us to understand how this material is replicated. Prior to this, it was thought that protein was the genetic information. A string of nucleotides has less information content than an amino acid string of the same length. Dna replication is addition of nucleotides following a template. The addition of nucleotides always occurs at a 3" oh. At the 5" end, there is a phosphate. Dna polymerase only function is the addition of bases to the 3" oh end. A complimentary nucleotide interacts w/ polymerase and the complementary nucleotide. If the nucleotides are not complementary, then the nucleotide will not stay in the active site of polymerase. If it is complementary, then a reaction takes place where two of the phosphates are hydrolyzed and removed. You are left with one phosphate in between each nucleotide to form the backbone of that dna strand. We know more about the bacterial system.