Biology 1202B Lecture Notes - Lecture 12: Silent Mutation, Alternative Splicing, Reading Frame
27 Feb 2017
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Document Summary
Many similarities between dna replication and transcription but must keep them separate. We generally think of transcription as the first step in protein production: functional products of transcription also include rna molecules. Histones + charge: dna charge, histone octamer. Nucleosome: dna wrapped around histone octamer (~2x) Histone tails are sites of chemical modification: chromatin remodelling. Inactive x in males: loosely packed available for transcription. Each step in arginine synthesis controlled by a gene which codes for the required enzyme. Proteins often contain more than one polypeptide. A region of dna which is transcribed. The region(s) of dna which are required for transcription: dna binding sites for regulatory molecules, gene transcription is a highly regulated process, genes only turned on when necessary. February 15, 2017: template reads 3" 5", mrna is identical to non-template. Mrna read as 3 nucleotide codons (amino acid) 61 codons 61 specify amino acids: start codons does, stop codons do not. Degenerate: more than one codon/amino acid.
