Biology 1202B Lecture Notes - Lecture 12: Histone Octamer, Histone H1, Start Codon
11 Feb 2016
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Biology 1202b: lecture 12 transcription and translation i. Many similarities between dna replication and transcription keep them separate. We generally think of transcription as the first step in protein production: functional products of transcription also include rna molecules. The more densely packed the chromatin the less likely it is to be transcribed. Histones + charge: dna charge, histone octamer. Histone tails are sites of chemical modification: chromatin remodelling. Loosely bound dna is more available for transcription. Dna is always in form of dna + protein = chromatin. Histone is a protein: binds to nucleosomes and linker dna, causing nucleosomes to form coiled structure. Histone h1 binding: 30 nm fiber. Densely packed with proteins silent: euchromatin. Each step in arginine synthesis controlled by a gene which codes for the required enzyme. Hemoglobin molecule: has 4 subunits needs all of them to function, main oxygen carrying component in red blood cells. A region of dna which is transcribed.
