Chemistry 2213A/B Lecture Notes - Lecture 3: Hydrophile, Amine, Dipeptide

• School: Western University
• Department: Chemistry
• Course: Chemistry 2213A/B
• Professor: Mark Workentin

Document Summary

Peptide bond is a type of amide bond that connects amino acids together. The bond is formed between alpha amino group of one acid with the carboxyl group of another. 2 amino acids together is dipeptide. multiple amino acids results in polypeptide. The 2 ends of the peptide bond are different resulting in polarity. One end is the n-terminal, it has a free amino group. The other end is c-terminal, it has a free carboxyl group. Polypeptides are elongated by adding the amino acids to the c-terminal. When writing out the polypeptide n-terminal is written before c-terminal. ex. ser-gly (sg) isn"t the same as gly-ser (gs). The repeating pattern of amino acids is known as the backbone of the peptide. Peptide bond is single bond but has double bond characteristics due to resonance between c-o. This means that 6 atoms are coplanar and there is no free rotation around c-n axis so its less flexible and prevents some folding patterns.