Chemistry 2223B Lecture Notes - Doxorubicin, Fischer Projection, Stereochemistry

• School: Western University
• Department: Chemistry
• Course: Chemistry 2223B
• Professor: James Wisner

Document Summary

Chemistry 2223b winter 2013 14 western university. This chapter discusses the fundamental chemistry and properties of carbohydrates, emphasizing on monosaccharides. The mechanistic chemistry of the metabolism of glucose into pyruvate (glycolysis) is also introduced. Background material that is important includes: stereochemistry, enantiomers and diastereomers, fischer projections, reactions of alcohols, carbonyl compounds, and carboxylic acids. Oxidation and reduction: biological significance and categories of carbohydrates. Carbohydrates are the most abundant, naturally occurring class of biomolecules: they constitute half of the world"s biomass (dry weight). They are made primarily by plants via photosynthesis. Hence, they serve as a mechanism of energy storage. Light energy + co2 + h2o carbohydrates + o2. Carbohydrates also have structural roles, such as cellulose and chitin. They are also components of some drugs, such as salicin (willow bark) and adriamycin (streptomyces achromogenes). Ohohoohoohch2ohoonh2ohh3cooch3oohohoch2ohsalicinadriamycin carbohydrates are found as components of not only small biomolecules, but also in large, high-molecular-weight biopolymers.