Microbiology and Immunology 3300B Lecture Notes - Lecture 2: Small Cell, Nucleated Red Blood Cell, Haematopoiesis
20 May 2016
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Document Summary
Basement membranes support the epithelial cells because cells are very squishy: the basement membrane is thick and fibrous: it is tough and flexible. Unique to our lung: we have hair like extensions called cilia that push mucus away from the cell: pushes mucus into the trachea where we can swallow it, mucus traps pathogens. Lysozymes degrade the cell wall membranes of bacteria. Phospholipase breaks down the lipid phospholipid bilayer of bacteria. Gram positive bacteria also have peptidoglycan which is a thick extra layer: this is why you need lysozyme and phospholipase to kill a bacteria. Used for fungi and gram negative bacteria. <1% leukocytes (4-10e6/ml) and platelets: called the buffy coat, contains pmns these cells have weird looking nuclei e. g. neutrophils (50-65%) eosinophils (1-4%) basophils (0. 5-1%, contain mononuclear cells. Immune cells are formed in the bone marrow. T cells undergo further development in the thymus.
