Microbiology and Immunology 3820A Lecture 10: micro imm- week 10

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Mycobacteria classification: tubercle bacilli complex, mott (mycobacteria other than tubercle bacilli, non tuberculosis mycobacteria, mycobacterium leprae (causal agent of leprosy, tuberculosis complex, mycobacterium tuberculosis, mycobacterium bovis, mycobacterium africanum, mycobacterium canettii, mycobacterium microti, mycobacterium caprae. Tuberculosis: (cid:883)/(cid:885) of the world"s population infected, ~30 million active cases. If the sputum stains negative for afb patient is noninfectious. Incidence of tb is low in north america except in first nations, inuit, refugees, aids and the homeless: almost eradicated tb but cut off the funding, some hiv patients then increased the number. Already gotten latent tb: anything that makes you lose weight (involuntary) Chest x-rays: tb: apical abnormality, arrows not usually on the x-rays. Mantoux test: intradermal injection of 5 tuberculin units of ppd: purified protein derivative, very shallow, hold skin tight. Induration (not erythema or redness) is measured in mm 48-72 hours later.

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