Microbiology and Immunology 3820A Lecture Notes - Lecture 13: Egg Cell, Neonatal Conjunctivitis, Tropism
4 Mar 2016
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Neisseria gonorrhoeae infection syndromes (dr. colby) lecture 7 - nisseria. Neisseria gonorrhoeae colby never had gonorrhaeae. Named after german physician a. l. s. Neisser, who first described the organism. Gram negative diplococci, usually intracellular. Fastidious: needs special enriched media and co2. Does not tolerate desiccation or cold. Hypersensitive to temp extremes (cold) and drying. Only way to get this is to put tissue against another mucosal tissue. Oxidizes glucose, but not maltose nor lactose. Por a protein (porin protein) type a bearing strains resist serum killing. Opa proteins (opacity proteins) mediate adherence bery adherent to our tissue. Rmp proteins (reduction modifiable proteins) stimulate ab that block other factors of serum killing. Organism expresses antigens that induce a blocking immune response in its host. Los (lipo- oligosaccharide) has lipid a & co. Pilin protein (pili) mediates initial attachment. Urethritis (males and females)/ cervicitis (main syndrome that women get endocervix that gets infected with nes.
