Pathology 3245B Lecture Notes - Lecture 11: Pulse Pressure, Diastole, Perfusion

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Blood pressure 120/80 (pressure exerted by circulating blood on walls or blood vessels) measured in mmhg. Systolic (upper number: pressure during heart contraction (highest pressure the heart or aorta can have) Diastolic (lower number: pressure during relaxation phase while heart is filling (time of diastole) Pressure between contractions: longer duration heart exposed to this pressure for longer period of time. Therefore, more important clinically than systolic bp. Pulse pressure: difference between systolic and diastolic pressure (e. g. 120/80 pulse pressure = 40: pulse pressure = systolic pressure diastolic pressure. Diastolic pressure: important clinically because it"s a perfusion pressure. Mean pressure in average person is 80 + [1/3 x (120 80)] = ~93 mmhg. Sufficient for tissue to get enough oxygen and blood. Highest pressure in lv and almost same pressure in aorta. As you go through peripheral circulation, capillaries, and venous circulation, pressure goes down. Almost 0 when it reaches the right atrium.

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