Pathology 3245B Lecture Notes - Lecture 9: Urinary Tract Infection, Urinary Retention, Bladder Stone
25 May 2016
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Document Summary
Retrograde of urine resulted in back pressure; little area of dilatation; Grade the degree of abnormality depending on how much dilataion (severe back pressure) and how severe the is. Lodge themselves into renal pelvis and can calices molding into shape. Composition: calcium 75, struvite 15% (mix of salts, uric acid 6, cistine 2, other 2% Pathophysiology: increase concentration of stone-forming constituents, decrease production of stone inhibiting buffer agents. Etiology: hereditary predisposition, underlying medical condition (e. g. hypercalcuria, gout, low fluid intake dehydration, urinary tract infections (urea splitting bacteria struvite stones, urinary flow abnormalities, diet in at risk population. Body secreting too much salt; not secreting enough salt buffering agents. If stones are big, might need surgical removal. Material forming this most commonly is struvite chronic obstruction. Patient at risk for chronic urinary tract infection cortex atrophy (where filtration occurs; scarring down filtration capability)
