Pathology 3245B Lecture Notes - Lecture 1: Oncotic Pressure, Blood Sugar, Starling Equation
Document Summary
Blood flow normal fluid homeostasis: edema, hyperemia, hemorrhage. Maintenance of blood as a liquid: thrombosis. 60% of a person"s body weight is water. Introduction survival of cells and tissue is dependent on: oxygen provided in the blood supply, normal fluid balance normal fluid balance depends on, starling"s law, systemic factors. Process of maintaining a constant internal environment despite changing external conditions. Change in net movement of water across the vascular wall. Each day, about 50% of the total blood proteins leak out of the capillaries into the tissue fluid and return to the blood via the lymphatic vessels. Under normal circumstances, only a small amount of fluid leaks from vessels to form interstitial fluid, which is removed by lymphatic vessels. Starling"s law: movement of fluid between vascular and interstitial spaces (at level of capillaries) is controlled by 4 forces: 32 mmhg at the arteriolar end and 12 mmhg at the venous end.