Pathology 3245B Lecture Notes - Lecture 3: Luxol Fast Blue Stain, Multiple Sclerosis, Grey Matter
25 May 2016
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Increased risk w/ smoking, vit d deficiency. Ms risk throughout your life if you move (grew up in canada till late childhood before puberty) to equatorial you"ll take on equatorial region risk of ms and vice versa env"tal point. Ms plaques border lateral ventricles (common); variable in size, scattered through both hemispheres; curious morphology. Where is the world"s largest ms clinic london, ontario. Histological plaque acute ms plaque: imitate other things, may present as mass lesion to the individual (tumor or abscess) Appearance on imaging may not be distinguishing enough. Injury relatively discrete, picking up myelin sheath (still axons present?) If an infarct or core of abscess, everything would be gone, axons and myelin gone. Alcohol: peripheral neuropathy, cerebellar degeneration, seizures (from withdrawal in alcoholics, wernicke-korsakoff syndrome. More of a nutritional problem, byproduct of alcoholics not eating healthy and therefore not getting the vitamins. Street drugs: e. g. cocaine intracerebral hemorrhage.
