Pathology 3245B Lecture Notes - Lecture 4: Bone, Rheumatoid Arthritis, Metabolic Bone Disease
Document Summary
Hematopoiesis precursors that make blood cells. Long tubular bones: diaphysis (main shaft, metaphysis (where bone spreading out, growth plate (during development, allows for growth, end is epiphysis. Knowing these helps to determine most common disease in these specific areas. All have same histology, same building blocks (going from outside to inside) Hard shell on outside (compact bone) very dense; main function: structural (structural. Open in center, more blood, greater surface area for exchange of ca++ and. Bone is one of the few organs that can heal completely (no evidence of damage) Perisosteum elongated cells that are dormant and when stimulated can be very active. Bone mixture of materials (lots of collagen, other proteins that become mineralized, largely calcium and phosphate) As bone grows, some of it gets resorbed a bit. Hole = large blood vessel; cells arranged around this hole (osteocytes?) These cells will cross talk with another finger-like extensions.