Pathology 2420A Lecture Notes - Lecture 9: Polycystic Kidney Disease, Glomerular Basement Membrane, Chronic Kidney Disease
9 Dec 2016
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Document Summary
Module 9 diseases of kidney and urinary tract acute tubular necrosis (atn) - necrosis and death of tubular cell, generally due to a lack of oxygen or exposure to toxins. Primary glomerulopathies are diseases which affect the glomerulus primarily or exclusively. Tcc is most common in the bladder, but can occur in the renal pelvis or ureters as well. Usually broken down into two types - low grade (papillary, superficial and slow growing) and high grade (deeply invasive, aggressive, metastases). Kidneys filter 1700 l of blood to produce 1 l of urine every day. Makeup 0. 5% of body weight, receive 25% of blood supply that is pumped form heart. Perform the following functions: elimination of drugs, toxins, poisons, and metabolic waste products from blood, homeostasis. Maintenance of proper serum electrolyte concentrations (na) Regulation of blood pressure (through na and h2o balance, renin production: hormonal activity.
