Pathology 2420A Lecture Notes - Lecture 3: Cellulitis, Foreign Body, Cell Adhesion Molecule

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After injury, a series of reactions will occur at the site of injury called an inflammatory reaction. Characteristic response of living tissues to an injury. The intensity, duration and outcome of the infam reaction are modified by factors pertaining to the host and injurious insult. Trauma penetrating injury (stab wound, wood sliver), blunt trauma, thermal injury (heat or cold), chemical injury (acid or alkali) Loss of blood supply (ischemia) * inflammation doesn"t equal infection. Infection almost always will cause inflame reaction. However, inflame reactions are diverse (more then just infection from microorganism). Usually, a large infam reaction will occur in response to infection. Inflammation can be broken down into event : vascular and cellular, both mediated by chemical factors (mediators). Arterial venous shunts in capillary bed. Sometimes causes stasis or thrombosis (clotting). These cells contain myofibrils within the cytoplasm and these allow for cell contraction.

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