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Canada (509,656)
Pharmacology (354)
Lecture

Module 3 Notes.docx

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Department
Pharmacology
Course
Pharmacology 2060A/B
Professor
Angela Nissen
Semester
Fall

Description
Module 3 NotesFREE DRUG distribution in compartments in body where STORED METABOLIZED EXERT or EXCRETED compartments o interstitial space extracellular fluid surrounds cellsLOW MOLECULAR WEIGHTWATER SOLUBLE DRUGS o Total body waterInterstitial space intracellular fluid and plasma o Plasma Non cell containing Drugs bound to plasma protein HIGH MOLECULAR WEIGHT o Adipose tissue bodies fatLipid soluble drugs o Muscle o BoneCrystal surface of bone into crystal latticeSLOW RELEASE OF DRUGS Drug distributionblood flow to tissues o rapid kidney liver brain WELL PERFUSED o slow muscle bone skinLOW BLOOD FLOWneonates babie
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