Pharmacology 2060A/B Lecture Notes - Lecture 1: Natural Health Product, Pharmacology, Tight Junction
9 Dec 2016
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Objectives: define pharmacology, understand naming system for drugs, understand drug regulations in canada, appreciate the barriers to drug transport, apply ph dependent ionization to drug transfer. Derived from the greek words pharmakon (remedy) and logos (study) study of. Includes various aspects including: how a drug is delivered (route of administration, how it works (mechanism of action, therapeutic effect of drugs on patients, adverse effects of drugs on patients. Classification: drugs traditional drugs (chemical agents, biologics antibodies, hormones, natural health products herbals, vitamins, minerals. Therapeutic products directorate approval of typical drugs (pills and tablets) Biologics and genetic therapies directorate evaluate and approve hormone and antibody therapies. Natural health products directorate approves and evaluate natural source medicine products. Chemical is what actually produces pharmacological effect. Example: chemical 7-chloro-1,3-dihydro-1-methyl-5-phenyl-1,4-benzodiazepin-2(2h)- one, generic diazepam. Enteral gi tracts: oral, rectal. Parenteral do not involve gi system, mostly injectable: intravenous, intramuscular, subcutaneous. Topical put on surface of skin: creams, patches. What the body does to the drugs.
