Pharmacology 2060A/B Lecture Notes - Lecture 2: Rugae, Drug Metabolism, Hypotension
4 Jan 2021
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Document Summary
Defined as the study of drug movement in the body. Is what the body does to the drug. Pharmacokinetics is composed of four basic processes . Drug absorption is the movement of the drug from the site of administration into the blood. The rate of absorption determines how quickly the drug effect will occur. The amount of drug absorption determines how intense the effect of the drug will be. Drugs must dissolve before they can be absorbed. Drugs with a fast rate of dissolution will have a faster onset of action than drugs with slow dissolution. The example on the right shows drugs placed in a liquid. Over time, dissolution occurs and the drug molecules are dissolved in the liquid. The same thing happens when we swallow a medication the tablet undergoes disintegration and the medication dissolves in out stomach contents. Surface area is a major determinant of drug absorption. The larger the surface area, the faster drug absorption is.
