Pharmacology 2060A/B Lecture Notes - Lecture 1: Postmarketing Surveillance, Tight Junction, Golgi Apparatus
3 Mar 2016
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Module 1 - introduction to pharm: Naming of drugs (3 types of names): Approval of marketed drugs in canada (7) Biologics antibodies, hormones: natural health products herbs, vits, minerals. Food + drugs act & reg health canada health canada products & Food branch therapeutic products directorate, biologics & genetic. Therapies directorate, natural health products directorate. Molecules of chemicals, not just a pill or capsule. Chemicals produces the pharmacological effect. Chemical name describes chemical structure of mol"c. Used by chemists, not others. Generic name unique name that identifies drug. Should be used by hps, tho not. Trade name drug company name. Example: diazepam (generic), valium (trade) Preclinical testing in cultured cells, living tissue or animals. Look at effects, toxicity etc. Clinical trial application submitted to hc before human studies. Phase 1 clinical trial 20- 100 healthy volunteers, evaluation. Phase 2 clinical trial 300- 500 pts with disorder, effects etc. If approved need noc (notice of compliance) and din (drug identification number).
